Formulation and Particle Size Reduction Improve Bioavailability of Poorly Water-Soluble Compounds with Antimalarial Activity

Figure 4

Concentration versus time profiles of DQ in mice liver following single oral dose of nanoparticles in aqueous solution (0.39 µm, red solid line) and microparticle suspension in HECT in distilled water (36.88 µm, blue dashed line).