Formulation and Particle Size Reduction Improve Bioavailability of Poorly Water-Soluble Compounds with Antimalarial Activity

<table>Different ratios of phosphatidylcholine (PC) to DQ were used in solid dispersion in the presence of polyvinylpyrrolidone 10 (PVP 10 : DQ = 6 : 1, w/w).  After removal of solvents, dry film was suspended in water and subjected to particle size reduction by sonication and then HPH.  </table>

Malaria Research and Treatment

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Figure 6

Figure 6: Formulation and Particle Size Reduction Improve Bioavailability of Poorly Water-Soluble Compounds with Antimalarial Activity 