Formulation and Particle Size Reduction Improve Bioavailability of Poorly Water-Soluble Compounds with Antimalarial Activity

Table 1

Particle size (μm) measurements of DQ in water or HECT suspension stored at 4°C.

Stability duration	Methods
	HG	US	SD plus HPH
Week 1	99.23	36.62	0.401
Week 2	101.33	36.97	0.384
Week 3	105.56	36.92	0.377
Mean	102.04	36.88	0.392

SD: solid dispersion; HG: homogenizer with generator; US: ultra-sonicator; HPH: high pressure homogenization.