Research Article
A Pharmacokinetic Study of Antimalarial 3,5-Diaryl-2-aminopyridine Derivatives
Table 1
Mass spectrometer settings and MS parameters used for the detection of the test compounds on an API 3200 Q-Trap.
| | Parameter | Compound 1 | Compound 2 |
| | Q1 mass (Da) | 428.1 | 408.9 | | Q3 mass (Da) | 227.2 | 315.2 | | Dwell time (msec) | 40 | 40 | | Declustering potential | 81 | 101 | | Collision energy (Volts) | 77 | 55 | | Entrance potential (Volts) | 10 | 10 | | Collision cell exit potential (Volts) | 4 | 2 | | Source temperature | 500°C | 500°C | | Curtain gas (psi) | 25 | 25 | | Gas 1 (psi) | 50 | 50 | | Gas 2 (psi) | 70 | 70 | | CAD gas | Medium | Medium | | Ion spray voltage (kVolts) | 5500 | 5500 | | Ionization mode | Positive | Positive |
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