Retinal Damage in Multiple Sclerosis Disease Subtypes Measured by High-Resolution Optical Coherence Tomography

Table 1

Demographic and clinical data of multiple sclerosis patients (MS) and healthy controls (HC). MS patients are subdivided in the subtypes relapsing-remitting MS (RRMS), secondary-progressive MS (SPMS), and primary-progressive MS (PPMS).

		HC	MS
			RRMS	SPMS	PPMS	All MS
No. of Subjects	Total	94	308	65	41	414
	Berlin	63	95	22	8	125
	Hamburg	0	158	23	22	203
	Düsseldorf	31	55	20	11	86
No. of Eyes (eyes with ON)	Total	183	561 (156)	116 (27)	77 (0)	754 (183)
	Berlin	122	187 (77)	44 (15)	16 (0)	247 (92)
	Hamburg	0	270 (54)	35 (2)	41 (0)	346 (56)
	Düsseldorf	61	104 (25)	37 (10)	20 (0)	161 (35)
Gender	Male (%)	31 (33)	87 (28)	29 (45)	24 (59)	140 (34)
	Female (%)	63 (67)	221 (72)	36 (55)	24 (41)	274 (66)
Age (in years)	Mean (SD)	34.47 (10.25)	39.10 (9.50)	48.23 (6.11)	46.90 (7.10)	41.31 (9.59)
	Range	19–56	19–58	33–59	32–59	19–59
Disease duration (in months)	Mean (SD)	NA	91.05 (80.26)	186.15 (87.94)	100.02 (93.33)	106.87 (89.51)
	Range	NA	0–384	39–403	4–426	0–426
EDSS	Median	NA	2.0	5.5	4.0	2.5
	Range	NA	0-7	3-8	2-8	0-8