Retinal Damage in Multiple Sclerosis Disease Subtypes Measured by High-Resolution Optical Coherence Tomography

Table 5

Generalized estimation equation (GEE) models correlating disease duration with RNFL thickness and TMV, respectively. The yearly change based on the effect sizes of the respective GEE model.

	RNFL thickness				TMV
	Effect size	SE	𝑃 value	Change per year (𝜇m)	Effect size	SE	𝑃 value	Change per year (mm³)
All MS-NON	−0.0444	0.0068	<0.001	−0 .533	−0.0012	0.0002	<0.001	−0 .014
RRMS-NON	−0.0413	0.0088	<0.001	−0 .495	−0.0013	0.0003	<0.001	−0 .016
SPMS-NON	−0.0387	0.0174	0.026	−0 .464	−0.0001	0.0006	0.838	−0 .002
PPMS-NON	−0.0088	0.0151	0.562	−0 .105	−0.0009	0.0006	0.131	−0 .011