Brain Abnormalities in Neuromyelitis Optica Spectrum Disorder

Figure 3

Paired fluid-attenuated inversion recovery (FLAIR) (left) and corresponding gadolinium-enhanced (right) axial images of patients who showed enhancement. Enhancement observed in extensive hemispheric lesions (A, B, and E) and periependymal lesions surrounding the lateral ventricles (C, D). The lesions reveal multiple patchy enhancement patterns with blurred margins, showing typical “cloud-like enhancement”. One exceptional lesion reveals well-marginated nodular enhancement at an extensive hemispheric lesion (E) [28].