Table 1: Demographic and clinical characteristics in severely fatigued MS patients with and without sleep-disordered breathing.

No SDB (AHI < 5/h)SDB (AHI ≥ 5/h)P

n (%)41 (59%)28 (41%)
Female sex, n (%)32 (78%)16 (57%)0.06
Age (y)47.4 ± 8.353.3 ± 9.50.01
BMI25.4 ± 5.226.8 ± 4.20.27
Disease duration (y)13.8 ± 8.913.6 ± 8.80.92
Disease subtype0.73
 RRMS36
 SPMS2535
EDSS5.9 ± 1.55.8 ± 1.30.79
FSS5.7 ± 0.75.5 ± 0.90.36
ESS9.4 ± 4.79.7 ± 3.80.79
EDS (ESS ≥ 10)18 (44%)17 (61%)0.13

BMI: body mass index (kg/m2), EDS: excessive daytime sleepiness, EDSS: Expanded Disability Status Scale, ESS: Epworth Sleepiness Scale, FSS: Fatigue Severity Scale, RRMS: relapsing-remitting multiple sclerosis, SPMS: secondary progressive multiple sclerosis.