Clinical Study

Assessing Relapse in Multiple Sclerosis Questionnaire: Results of a Pilot Study

Table 5

Total Composite Score, Activities of Daily Living Score, and Return to Previous State of Health Score.

Patients Completing Part 2 of ARMS Questionnaire value*
Total ( = 103)Corticosteroids ( = 90)ACTH ( = 13)

TCS after relapse, mean (SD) ( = 100)18.51 (7.6)18.92 (7.4)15.77 (8.8)0.166
ADL score, mean (SD)
 Part 1—New relapse ( = 103)3.38 (2.1)3.43 (2.1)3.00 (1.9)0.483
 Part 2—After relapse treatment ( = 103)6.21 (2.7)6.34 (2.7)5.31 (2.8)0.198
 Change ( = 103)2.83 (2.8)2.91 (2.9)2.31 (2.4)0.478
RSH score, mean (SD)
 Part 1—New relapse ( = 90)7.22 (2.5)7.33 (2.3)6.50 (3.3)0.283
 Part 2—After relapse treatment ( = 100)6.00 (3.0)6.15 (3.0)5.00 (3.2)0.201
 Change ( = 87)−1.11 (2.6)−1.03 (2.7)−1.67 (2.2)0.438
PCS, mean (SD)
 Part 1—New relapse ( = 90)10.52 (3.6)10.69 (3.4)9.42 (4.6)0.251
 Part 2—After relapse treatment ( = 100)12.38 (5.2)12.69 (5.0)10.31 (6.0)0.123
 Change ( = 87)2.07 (4.4)2.29 (4.5)0.67 (3.4)0.233

values based on test comparing corticosteroids and ACTH treatment groups.
values for RSH and PCS are lower due to patients who did not respond to these questions in Part 1 ( = 13 patients who indicated no treatment or not sure of treatment for last relapse) or Part 2 ( = 3 patients in corticosteroids group who responded “got worse”, which was not assigned a numerical value).
ACTH: adrenocorticotropic hormone; ADL: activities of daily living; ARMS: Assessing Relapse in Multiple Sclerosis; PCS: partial composite score; RSH: return to previous state of health; SD: standard deviation; TCS: total composite score.