Table 2: Showing the clinical features of multiple sclerosis patients in Malaysia. (A subgroup analysis of demographics in NMO/NMOSD patients was also included.)


Female : male/%87 : 17 (83% : 17%) ( ratio: 5 : 1)
In the MS group:
Malays : Chinese : Indians : others
%

55/104 : 19/104 : 28/104 : 2/104 patients
52.9% : 18.3% : 26.9% : 1.9%
In the NMO/NMOSD group:
Malays : Chinese : Indians : others
%

38/77 : 32/77 : 7/77 : 0/77 patients
49.4% : 41.6% : 9.1% : 0%
Mean age at onset/years
Mean duration of illness/years
Site of involvement At onset     At first relapse
 Optic nerve37/104 (35.6%)    20/104 (19.2%)
 Spinal cord26/104 (25.0%)    33/104 (31.7%)
 Subcortical 23/104 (22.1%)    32/104 (30.7%)
 Brainstem and cerebellum18/104 (17.3%)    19/104 (18.4%)
Mean number of exacerbations
Annualized relapse rates/year
Mean EDSS at onset
Familial involvement5/104 (5%)
Clinical course
 RRMS93/104 (89.4%)
 SPMS6/104 (5.8%)
 PPMS5/104 (2.9%)
CSF (OCB %)38/66 (57.6%)
Ambulating independently (current status)78/104 (75%)
Visual acuity (20/30 and above) in one/both eyes94/104 (90.4%)
ANA positivity (1 : 40 to 1 : 80)4/104 (3.8%)
Initial brain MRI fulfills
 McDonald’s 2005 criteria for dissemination in space
 McDonald’s 2010 criteria for dissemination in space

64/104 (61.5%)
69/104 (66.4%)
Spinal multiple sclerosis4/104 (3.8%)

MS: multiple sclerosis; ANA: antinuclear factor, RRMS: relapsing-remitting multiple sclerosis; SPMS: secondary progressive multiple sclerosis; PPMS: primary progressive multiple sclerosis; OCB: oligoclonal bands; EDSS: expanded disability status scale.