627870.fig.003a
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627870.fig.003b
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Figure 3: Atrophy in multiple sclerosis as measured using Freesurfer (http://surfer.nmr.mgh.harvard.edu/). (a) Cortical and subcortical segmentation in a healthy control patient. (b) Cortical and subcortical segmentation in an age-matched patient with longstanding RRMS. Note the prominent subcortical, white matter, and neocortical atrophy in MS compared to healthy control.