2 weeks (5/week) real or placebo, followed by 2 weeks all real
Beneficial effect of repetitive transcranial magnetic stimulation combined with cognitive training for the treatment of Alzheimer’s disease: a proof of concept study [13]
8
6/8 had history of depression
75.4 ± 4.4
Probable early-moderate AD (Clinical Dementia Rating of 1)
6 regions (3 per day, every other day) (i) Broca, Wernicke and right DLPFC (ii) left DLPFC and right and left parietal somatosensory association cortex (pSAC)
10 Hz
90% for Broca and DLPFC, 110% for Wernicke and pSAC
6 weeks (5/week), followed by maintenance (2/week) for 3 months
Effects of low versus high frequencies of repetitive transcranial magnetic stimulation and functional excitability in Alzheimer’s dementia [12]