Determining the Optimal Number of Stimuli per Cranial Site during Transcranial Magnetic Stimulation Mapping

Table 1

Map volume data (in mV) for varying numbers of stimuli per cranial site.

Number of stimuli per cranial site	Median (IQR)	Mean difference with reference standard (95% CI)	ICC (95% CI)
One	14.20 (8.18 to 24.07)	2.85 (0.90 to 4.79)	0.90 (0.62–0.96)
Two	12.08 (6.83 to 18.30)	0.11 (−0.38 to 0.60)	0.99 (0.99–0.99)
Three	14.07 (7.09 to 20.34)	0.73 (0.11 to 1.36)	0.99 (0.96–0.99)
Four	12.92 (6.89 to 19.70)	0.37 (0.08 to 0.67)	0.99 (0.99–0.99)
Five	12.52 (6.61 to 18.43)	NA	1.00 (NA)

Key: IQR = interquartile range, ICC = intraclass correlation coefficient with five stimuli per cranial site (the “true” value), CI = confidence interval, and NA = not applicable.