Review Article

Regulation of EPCs: The Gateway to Blood Vessel Formation

Table 1

Regulation of EPC phenotype.

Endothelial markersAdhesion moleculesProgenitor markersReferences

Stimulation
 GATA2↑CD31, vWF↑CD117[81, 85]
 Id1↓CD144, vWF↓CD133, CD34[96]
 PPAR↑CD31, CD144↑ICAM-1[106]
 PPAR↑CD144, vWF↓ICAM-1, VCAM-1[116, 121]
 Nanog↓CD31, CD144, vWF[134, 136]
Inhibition
 Id1↑ Integrin α4[88]

vWF: von Willebrand factor; ICAM-1: intercellular adhesion molecule-1; VCAM-1: vascular cell adhesion molecule-1.