Review Article
Regulation of EPCs: The Gateway to Blood Vessel Formation
Table 1
Regulation of EPC phenotype.
| | Endothelial markers | Adhesion molecules | Progenitor markers | References |
| Stimulation | | | | | GATA2 | ↑CD31, vWF | | ↑CD117 | [81, 85] | Id1 | ↓CD144, vWF | | ↓CD133, CD34 | [96] | PPAR | ↑CD31, CD144 | ↑ICAM-1 | | [106] | PPAR | ↑CD144, vWF | ↓ICAM-1, VCAM-1 | | [116, 121] | Nanog | ↓CD31, CD144, vWF | | | [134, 136] | Inhibition | | | | | Id1 | | ↑ Integrin α4 | | [88] |
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vWF: von Willebrand factor; ICAM-1: intercellular adhesion molecule-1; VCAM-1: vascular cell adhesion molecule-1.
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