Dopaminergic Suppression of Synaptic Transmission in the Lateral Entorhinal Cortex
Figure 5
Dopamine suppresses
both the fast and slow components of the mixed monosynaptic IPSP in fan
cells. (a) GABA-mediated IPSPs were
isolated pharmacologically with ionotropic glutamate receptor blockers and
recorded at membrane potentials just below action potential threshold. Both the early (circle) and late (square)
components of the biphasic IPSP were suppressed by 50 M dopamine (DA). (b) Group data reflect a significant suppression
of both the early and late IPSPs.
