Research Article

Differential Induction of Long-Term Potentiation in the Horizontal versus Columnar Superficial Connections to Layer II Cells of the Entorhinal Cortex

Figure 2

Afferent independence between the ascending columnar and horizontal associational pathways. The two pathways were stimulated repetitively (left panels) or alternatively (right panels) using a short interpulse interval (60 milliseconds). Each trace represents an average of 16 sweeps. Although paired-pulse facilitation (PPF) was observed in both (a) the ascending and (b) horizontal pathways when stimulated independently (right panels), no facilitation was observed when stimulating each alternatively (left panels). Dotted lines indicate the maximum amplitude to the first pulse in each case.
814815.fig.002a
(a)
814815.fig.002b
(b)