Differential Induction of Long-Term Potentiation in the Horizontal versus Columnar Superficial Connections to Layer II Cells of the Entorhinal Cortex
Figure 3
LTP in the horizontal associative
pathway of the superficial entorhinal cortex. The stimulation electrode was
positioned on the surface of layer I, lateral to the recording electrode. (a) Normalized scaled amplitude of peak
EPSCs evoked by test pulses in a layer II cell is plotted against time. HFS at
time zero led to an immediate and long-lasting potentiation of EPSCs. The inset
shows two traces reflecting averaged EPSCs at baseline (pre-HFS) and at 30
minutes post-HFS. (b) Average
normalized scaled amplitude of peak EPSCs across 15 cells. The value at 30
minutes post-HFS () is significantly different from baseline ().
