Research Article

The Role of NMDA Receptor Subtypes in Short-Term Plasticity in the Rat Entorhinal Cortex

Figure 1

Short-term facilitation is mediated by presynaptic NMDA receptors. (a) First 6 responses evoked by a train of stimuli (3 Hz, 20 seconds) averaged from 3 neurones. (b) Responses ( ) were averaged at low frequency and during 3 Hz stimulation. In the presence of 2-AP5, low-frequency responses were unaltered, but facilitation was abolished. The bar graphs show the mean results from 5 neurones. (c) Similar results were seen with MK-801. Stimulation artifacts have been partially blanked for clarity.
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(a)
872456.fig.001b
(b)
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(c)