Review Article

The Role of the Periaqueductal Gray in the Modulation of Pain in Males and Females: Are the Anatomy and Physiology Really that Different?

Figure 2

(a)–(c) Distribution of cells retrogradely labeled (FG+) from the RVM in males (left) and females (right) at three representative rostrocaudal levels of the periaqueductal gray. Each black circle represents one FG+ cell. (d)–(f) Distribution of PAG cells that were immunoreactive for AR (closed circles) or ER (open circles). (g)–(i) Distribution of PAG cells retrogradely labeled from the RVM that were also immunoreactive for AR (closed stars) or ER (open stars).
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