Review Article

Contributions of Matrix Metalloproteinases to Neural Plasticity, Habituation, Associative Learning and Drug Addiction

Figure 2

Mean ( SEM) group changes in head-shake responses (HSR) per three-trial blocks during sessions I and II. These sessions were separated by 5 minutes, 2, 6, or 24 hours, respectively. There were no differences among these groups comparing the first trial blocks of Session I. Each group significantly differed from the others comparing the first trail blocks of Session II. Specifically, the 5 minute ISI group indicated very little spontaneous recovery suggesting excellent memory retention of the habituatory response. The 2 and 6 hours ISI groups showed increments in spontaneous recovery and thus some loss of memory retention, while the 24-hour ISI group revealed 95% spontaneous recovery suggesting nearly complete loss of memory retention for habituation of the HSR, * , modified from Wright et al. [115].
579382.fig.002