- About this Journal ·
- Abstracting and Indexing ·
- Aims and Scope ·
- Article Processing Charges ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Recently Accepted Articles ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Volume 2009 (2009), Article ID 730902, 8 pages
Progesterone Withdrawal-Evoked Plasticity of Neural Function in the Female Periaqueductal Grey Matter
Department of Physiology, University of Birmingham, Birmingham B15 2TT, UK
Received 30 May 2008; Accepted 30 July 2008
Academic Editor: Robert Adamec
Copyright © 2009 T. A. Lovick and A. J. Devall. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- S. Matsumoto, M. C. Levendusky, P. A. Longhurst, R. M. Levin, and W. R. Millington, “Activation of mu opioid receptors in the ventrolateral periaqueductal gray inhibits reflex micturition in anesthetized rats,” Neuroscience Letters, vol. 363, no. 2, pp. 116–119, 2004.
- L. F. Hayward, C. L. Swartz, and P. W. Davenport, “Respiratory response to activation or disinhibition of the dorsal periaqueductal gray in rats,” Journal of Applied Physiology, vol. 94, no. 3, pp. 913–922, 2003.
- C. Sánchez, “Stress-induced vocalisation in adult animals. A valid model of anxiety?” European Journal of Pharmacology, vol. 463, no. 1–3, pp. 133–143, 2003.
- H. C. Salzberg, J. S. Lonstein, and J. M. Stern, “ receptor regulation of kyphotic nursing and female sexual behavior in the caudal ventrolateral periaqueductal gray of postpartum rats,” Neuroscience, vol. 114, no. 3, pp. 675–687, 2002.
- A. P. C. Guimarães and W. A. Prado, “Pharmacological evidence for a periaqueductal gray-nucleus raphe magnus connection mediating the antinociception induced by microinjecting carbachol into the dorsal periaqueductal gray of rats,” Brain Research, vol. 827, no. 1-2, pp. 152–159, 1999.
- P. Walker and P. Carrive, “Role of ventrolateral periaqueductal gray neurons in the behavioral and cardiovascular responses to contextual conditioned fear and poststress recovery,” Neuroscience, vol. 116, no. 3, pp. 897–912, 2003.
- A. P. Carobrez, K. V. Teixeira, and F. G. Graeff, “Modulation of defensive behavior by periaqueductal gray NMDA/glycine-B receptor,” Neuroscience and Biobehavioral Reviews, vol. 25, no. 7-8, pp. 697–709, 2001.
- T. A. Lovick and R. Bandler, “The organisation of the midbrain periaqueductal grey and the integration of pain behaviours,” in The Neurobiology of Pain, S. P. Hunt and M. Koltzenburg, Eds., Oxford University Press, Oxford, UK, 2005.
- S. M. Paul and R. H. Purdy, “Neuroactive steroids,” The FASEB Journal, vol. 6, no. 6, pp. 2311–2322, 1992.
- R. I. McLachlan, D. M. Robertson, D. L. Healy, H. G. Burger, and D. M. de Kretser, “Circulating immunoreactive inhibin levels during the normal human menstrual cycle,” Journal of Clinical Endocrinology & Metabolism, vol. 65, no. 5, pp. 954–961, 1987.
- M. Steiner, “Premenstrual syndromes,” Annual Review of Medicine, vol. 48, pp. 447–455, 1997.
- R. B. Fillingim and T. J. Ness, “Sex-related hormonal influences on pain and analgesic responses,” Neuroscience and Biobehavioral Reviews, vol. 24, no. 4, pp. 485–501, 2000.
- J. L. Riley III, M. E. Robinson, E. A. Wise, and D. D. Price, “A meta-analytic review of pain perception across the menstrual cycle,” Pain, vol. 81, no. 3, pp. 225–235, 1999.
- T. Bäckström, L. Andreen, V. Birzniece, et al., “The role of hormones and hormonal treatments in premenstrual syndrome,” CNS Drugs, vol. 17, no. 5, pp. 325–342, 2003.
- M. J. Zuluaga, D. Agrati, M. Pereira, N. Uriarte, A. Fernández-Guasti, and A. Ferreira, “Experimental anxiety in the black and white model in cycling, pregnant and lactating rats,” Physiology & Behavior, vol. 84, no. 2, pp. 279–286, 2005.
- M. Olsson, H.-P. Ho, K. Annerbrink, L. K. Melchior, J. Hedner, and E. Eriksson, “Association between estrus cycle-related changes in respiration and estrus cycle-related aggression in outbred female Wistar rats,” Neuropsychopharmacology, vol. 28, no. 4, pp. 704–710, 2003.
- F. K. Marcondes, K. J. Miguel, L. L. Melo, and R. C. Spadari-Bratfisch, “Estrous cycle influences the response of female rats in the elevated plus-maze test,” Physiology & Behavior, vol. 74, no. 4-5, pp. 435–440, 2001.
- G. Watanabe, K. Taya, and S. Sasamoto, “Dynamics of ovarian inhibin secretion during the oestrous cycle of the rat,” Journal of Endocrinology, vol. 126, no. 1, pp. 151–157, 1990.
- K. E. Brack and T. A. Lovick, “Neuronal excitability in the periaqueductal grey matter during the estrous cycle in female Wistar rats,” Neuroscience, vol. 144, no. 1, pp. 325–335, 2007.
- P. Robel and E.-E. Baulieu, “Neurosteroids: biosynthesis and function,” Critical Reviews in Neurobiology, vol. 9, no. 4, pp. 383–394, 1995.
- A. M. Hosie, M. E. Wilkins, H. M. A. da Silva, and T. G. Smart, “Endogenous neurosteroids regulate receptors through two discrete transmembrane sites,” Nature, vol. 444, no. 7118, pp. 486–489, 2006.
- W. J. Zhu and S. Vicini, “Neurosteroid prolongs channel deactivation by altering kinetics of desensitized states,” The Journal of Neuroscience, vol. 17, no. 11, pp. 4022–4031, 1997.
- A. E. Herbison, “Physiological roles for the neurosteroid allopregnanolone in the modulation of brain function during pregnancy and parturition,” Progress in Brain Research, vol. 133, pp. 39–47, 2001.
- M. D. Majewska, N. L. Harrison, R. D. Schwartz, J. L. Barker, and S. M. Paul, “Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor,” Science, vol. 232, no. 4753, pp. 1004–1007, 1986.
- T. A. Lovick, “GABA in the female brain—oestrous cycle-related changes in GABAergic function in the periaqueductal grey matter,” Pharmacology Biochemistry and Behavior, vol. 90, no. 1, pp. 43–50, 2008.
- S. S. Smith, Q. H. Gong, X. Li, et al., “Withdrawal from 3-OH-5-pregnan-20-one using a pseudopregnancy model alters the kinetics of hippocampal -gated current and increases the receptor 4 subunit in association with increased anxiety,” The Journal of Neuroscience, vol. 18, no. 14, pp. 5275–5284, 1998.
- P. J. Whiting, R. M. McKernan, and K. A. Wafford, “Structure and pharmacology of vertebrate receptor subtypes,” International Review of Neurobiology, vol. 38, pp. 95–138, 1995.
- P. Follesa, M. Serra, E. Cagetti, et al., “Allopregnanolone synthesis in cerebellar granule cells: roles in regulation of receptor expression and function during progesterone treatment and withdrawal,” Molecular Pharmacology, vol. 57, no. 6, pp. 1262–1270, 2000.
- P. Follesa, A. Concas, P. Porcu, et al., “Role of allopregnanolone in regulation of receptor plasticity during long-term exposure to and withdrawal from progesterone,” Brain Research Reviews, vol. 37, no. 1–3, pp. 81–90, 2001.
- I. Sundstrom-Poromaa, D. H. Smith, Q. H. Gong, et al., “Hormonally regulated GAB receptors are a target for alcohol,” Nature Neuroscience, vol. 5, no. 8, pp. 721–722, 2002.
- J. Griffiths and T. Lovick, “Withdrawal from progesterone increases expression of , , and GAB receptor subunits in neurons in the periaqueductal gray matter in female Wistar rats,” The Journal of Comparative Neurology, vol. 486, no. 1, pp. 89–97, 2005.
- J. L. Griffiths and T. A. Lovick, “GABAergic neurones in the rat periaqueductal grey matter express , and GAB receptor subunits: plasticity of expression during the estrous cycle,” Neuroscience, vol. 136, no. 2, pp. 457–466, 2005.
- T. A. Lovick and N. L. Paul, “Co-localization of GABA with nicotinamide adenine dinucleotide phosphate-dependent diaphorase in neurones in the dorsolateral periaqueductal grey matter of the rat,” Neuroscience Letters, vol. 272, no. 3, pp. 167–170, 1999.
- T. A. Lovick, J. L. Griffiths, S. M. Dunn, and I. L. Martin, “Changes in receptor subunit expression in the midbrain during the oestrous cycle in Wistar rats,” Neuroscience, vol. 131, no. 2, pp. 397–405, 2005.
- I. Mody, “Aspects of the homeostaic plasticity of receptor-mediated inhibition,” Journal of Physiology, vol. 562, no. 1, pp. 37–46, 2005.
- I. Mody, “Distinguishing between receptors responsible for tonic and phasic conductances,” Neurochemical Research, vol. 26, no. 8-9, pp. 907–913, 2001.
- R. Bandler and M. T. Shipley, “Columnar organization in the midbrain periaqueductal gray: modules for emotional expression?” Trends in Neurosciences, vol. 17, no. 9, pp. 379–389, 1994.
- T. A. Lovick, “Plasticity of receptor subunit expression during the oestrous cycle of the rat: implications for premenstrual syndrome in women,” Experimental Physiology, vol. 91, no. 4, pp. 655–660, 2006.
- R. Bandler, A. Depaulis, and M. Vergnes, “Identification of midbrain neurones mediating defensive behaviour in the rat by microinjections of excitatory amino acids,” Behavioural Brain Research, vol. 15, no. 2, pp. 107–119, 1985.
- C. L. Lu and U. Jürgens, “Effects of chemical stimulation in the periaqueductal gray on vocalization in the squirrel monkey,” Brain Research Bulletin, vol. 32, no. 2, pp. 143–151, 1993.
- M. M. Morgan and C. C. Clayton, “Defensive behaviors evoked from the ventrolateral periaqueductal gray of the rat: comparison of opioid and GABA disinhibition,” Behavioural Brain Research, vol. 164, no. 1, pp. 61–66, 2005.
- L. C. Schenberg, J. C. de Aguiar, and F. G. Graeff, “GABA modulation of the defense reaction induced by brain electrical stimulation,” Physiology & Behavior, vol. 31, no. 4, pp. 429–437, 1983.
- S. L. Jones and G. F. Gebhart, “Inhibition of spinal nociceptive transmission from the midbrain, pons and medulla in the rat: activation of descending inhibition by morphine, glutamate and electrical stimulation,” Brain Research, vol. 460, no. 2, pp. 281–296, 1988.
- L. A. Bee and A. H. Dickenson, “Rostral ventromedial medulla control of spinal sensory processing in normal and pathophysiological states,” Neuroscience, vol. 147, no. 3, pp. 786–793, 2007.
- C. J. Kovelowski, M. H. Ossipov, H. Sun, J. Lai, T. P. Malan Jr., and F. Porreca, “Supraspinal cholecystokinin may drive tonic descending facilitation mechanisms to maintain neuropathic pain in the rat,” Pain, vol. 87, no. 3, pp. 265–273, 2000.
- T. S. Jensen and D. F. Smith, “Effect of emotions on nociceptive threshold in rats,” Physiology & Behavior, vol. 28, no. 4, pp. 597–599, 1982.
- R. N. Walsh and R. A. Cummins, “The open-field test: a critical review,” Psychological Bulletin, vol. 83, no. 3, pp. 482–504, 1976.
- E. Jørum, “Analgesia or hyperalgesia following stress correlates with emotional behavior in rats,” Pain, vol. 32, no. 3, pp. 341–348, 1988.
- V. T. Martin, J. Lee, and M. M. Behbehani, “Sensitization of the trigeminal sensory system during different stages of the rat estrous cycle: implications for menstrual migraine,” Headache, vol. 47, no. 4, pp. 552–563, 2007.
- E. P. Vinogradova, D. A. Zhukov, and A. S. Batuev, “The effects of stages of the estrous cycle on pain thresholds in female white rats,” Neuroscience and Behavioral Physiology, vol. 33, no. 3, pp. 269–272, 2003.
- V. Kayser, K. J. Berkley, H. Keita, M. Gautron, and G. Guilbaud, “Estrous and sex variations in vocalization thresholds to hindpaw and tail pressure stimulation in the rat,” Brain Research, vol. 742, no. 1-2, pp. 352–354, 1996.
- M. Martínez-Gómez, Y. Cruz, M. Salas, R. Hudson, and P. Pacheco, “Assessing pain threshold in the rat: changes with estrus and time of day,” Physiology & Behavior, vol. 55, no. 4, pp. 651–657, 1994.
- C. A. Frye, C. A. Cuevas, and R. B. Kanarek, “Diet and estrous cycle influence pain sensitivity in rats,” Pharmacology Biochemistry and Behavior, vol. 45, no. 1, pp. 255–260, 1993.
- R. Hiroi and J. F. Neumaier, “Differential effects of ovarian steroids on anxiety versus fear as measured by open field test and fear-potentiated startle,” Behavioural Brain Research, vol. 166, no. 1, pp. 93–100, 2006.
- N. Eikelis and M. Van den Buuse, “Cardiovascular responses to open-field stress in rats: sex differences and effects of gonadal hormones,” Stress, vol. 3, no. 4, pp. 319–334, 2000.
- C. A. Frye, S. M. Petralia, and M. E. Rhodes, “Estrous cycle and sex differences in performance on anxiety tasks coincide with increases in hippocampal progesterone and ,-THP,” Pharmacology Biochemistry and Behavior, vol. 67, no. 3, pp. 587–596, 2000.
- S. Mora, N. Dussaubat, and G. Díaz-Véliz, “Effects of the estrous cycle and ovarian hormones on behavioral indices of anxiety in female rats,” Psychoneuroendocrinology, vol. 21, no. 7, pp. 609–620, 1996.
- C. N. Rudick and C. S. Woolley, “Estrogen regulates functional inhibition of hippocampal CA1 pyramidal cells in the adult female rat,” The Journal of Neuroscience, vol. 21, no. 17, pp. 6532–6543, 2001.
- M. M. Heinricher, M. E. Martenson, and M. J. Neubert, “Prostaglandin in the midbrain periaqueductal gray produces hyperalgesia and activates pain-modulating circuitry in the rostral ventromedial medulla,” Pain, vol. 110, no. 1-2, pp. 419–426, 2004.
- I. Marabese, F. Rossi, E. Palazzo, et al., “Periaqueductal gray metabotropic glutamate receptor subtype 7 and 8 mediate opposite effects on amino acid release, rostral ventromedial medulla cell activities, and thermal nociception,” Journal of Neurophysiology, vol. 98, no. 1, pp. 43–53, 2007.
- M. Fairhurst, K. Wiech, P. Dunckley, and I. Tracey, “Anticipatory brainstem activity predicts neural processing of pain in humans,” Pain, vol. 128, no. 1-2, pp. 101–110, 2007.