Table 5: Administration of drugs that act on the histaminergic system into the amygdala and memory performance.

SpeciesAmygdala siteBehavioral taskHistaminergic modulatorEffect on memoryReference(s)

RatBasolateralActive avoidanceHistamine [144]
RatBasolateralContextual fear conditioningH3 receptor antagonists (ciproxifan, clobenpropit and thioperamide) [154]
RatBasolateralContextual fear conditioningH3 receptor agonists (RAMH or Immepip) [144, 155]
RatBasolateralContextual fear conditioningH3 receptor agonist (proxifan)[156]

RAMH: (R)-(−)-alpha-methylhistamine.