Correlations between Hippocampal Neurogenesis and Metabolic Indices in Adult Nonhuman Primates

Figure 1

Representative images of histological studies of the dentate gyrus of hippocampus. (a) Granule cells in the subgranular zone (SGZ) positive (arrows) for DCX and Ki67. (A) represents negative control for DCX. (B) represents positive staining for DCX. (C) represents negative control for Ki67. (D) represents positive staining for Ki67. Scale bar: 100 μm. (b) Images of BCL2-labeled cells in the SGZ. BCL2 gene expression in the SGZ was rated using a semiquantitative according to a 4-point scale. (A) represents no labeling; rated as 0. (B) represents light labeling of individual cells; rated as 1. (C) represents heavy, yet noncontinuous labeling of BCL-2 along the SGZ; rated as 2. (D) represents intense labeling forming a continuous band along the entire length of the SGZ; rated as 3. Scale bar: 500 μm.