875307.fig.002a
(a)
875307.fig.002b
(b)
Figure 2: Correlation between in vivo adult body mass and postmortem measures of neurogenesis levels and BCL2 Expression. (a) shows a significant inverse correlation ( 𝑟 = 0 . 7 5 , 𝑃 = 0 . 0 3 , 𝑛 = 8 ) between body mass (in kilograms) and neurogenesis rates (indicated by the density of DCX-stained neurons with tertiary dendrites in per mm3 in the SGZ). Regression line of both groups combined not shown. (b) shows a significant, inverse correlation ( 𝑟 = 0 . 7 3 , 𝑃 = 0 . 0 4 1 , 𝑛 = 8 ) between body mass (in kilograms) and BCL2 expression in the SGZ (determined by a 4-point rating scale). Regression line of both groups combined not shown. These results show that animals with higher body mass have reduced neurogenesis rates and BCL-2. DCX: doublecortin; BCL-2: B-cell leukemia lymphoma 2. VFD: variable foraging demand (adversely-reared); LFD: low foraging demand (normally reared).