Mechanism of Repeat-Associated MicroRNAs in Fragile X Syndrome

Figure 2

Schematic representation of the mechanism of intronic miRNA expression. After transcription, the miRNA-containing intron is sliced out of the transcript; after further processing by the enzyme Dicer, mature miRNA is released and exported out of the nucleus. Meanwhile, the exons are linked together to form mature mRNA which is also transported out of the nucleus for translation.