Research Article

SCRAPPER Regulates the Thresholds of Long-Term Potentiation/Depression, the Bidirectional Synaptic Plasticity in Hippocampal CA3-CA1 Synapses

Figure 1

Inhibition of SCRAPPER protein expression in Scrapper-knockout (SCR-KO) mice. (a) Appearance of SCR-KO mice (Yao et al. [1], with permission from Elsevier). (b) Western blot analysis of SCRAPPER in wild-type (WT) or SCR-KO mouse hippocampus. Five microgram of protein in the hippocampal homogenate was applied to each lane and immunoblotted by the anti-SCRAPPER antibody. The SCRAPPER signal was not observed for SCR-KO mice. , WT; , heterozygote; , homozygote SCR-KO mice.
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