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Figure 2: Quantitative analysis of PSA-NCAM levels following graded-CCI. Short- and long-term changes in expression levels of PSA-NCAM in the eight brain regions evaluated using western blotting. Graphs depict mean PSA-NCAM density differences ± SEM of injury groups compared to the sham group (adjusted to mean = 1). Star color indicates statistical significance of difference between injury and sham values via one-way ANOVA and post hoc Tukey’s test (* , ** , *** ). Animal numbers per group (sham, moderate, severe) for each brain region are indicated in parentheses above the abscissa.