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Neural Plasticity
Volume 2012 (2012), Article ID 378307, 13 pages
http://dx.doi.org/10.1155/2012/378307
Research Article

Mouse Brain PSA-NCAM Levels Are Altered by Graded-Controlled Cortical Impact Injury

1Graduate Program in Neuroscience, F.E. Hébert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
2Department of Anatomy, Physiology, and Genetics, F.E. Hébert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
3Graduate Program in Molecular and Cell Biology, F.E. Hébert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
4Center for Neuroscience and Regenerative Medicine, F.E. Hébert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA

Received 29 February 2012; Revised 28 May 2012; Accepted 3 June 2012

Academic Editor: Yuji Ikegaya

Copyright © 2012 Craig S. Budinich et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. CDC, “Injury prevention & control: traumatic brain injury,” 2011, http://www.cdc.gov/traumaticbraininjury/statistics.html.
  2. S. Brown, G. Hawker, D. Beaton, and A. Colantonio, “Long-term musculoskeletal complaints after traumatic brain injury,” Brain Injury, vol. 25, no. 5, pp. 453–461, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. V. Rao and C. G. Lyketsos, “Psychiatric aspects of traumatic brain injury,” Psychiatric Clinics of North America, vol. 25, no. 1, pp. 43–69, 2002. View at Publisher · View at Google Scholar · View at Scopus
  4. T. Hampton, “Traumatic brain injury a growing problem among troops serving in Today's Wars,” Journal of the American Medical Association, vol. 306, no. 5, pp. 477–479, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. J. L. Pertab, K. M. James, and E. D. Bigler, “Limitations of mild traumatic brain injury meta-analyses,” Brain Injury, vol. 23, no. 6, pp. 498–508, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. H. G. Belanger, T. Kretzmer, R. Yoash-Gantz, T. Pickett, and L. A. Tupler, “Cognitive sequelae of blast-related versus other mechanisms of brain trauma,” Journal of the International Neuropsychological Society, vol. 15, no. 1, pp. 1–8, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. J. M. Ziebell and M. C. Morganti-Kossmann, “Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury,” Neurotherapeutics, vol. 7, no. 1, pp. 22–30, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. A. I. R. Maas, B. Roozenbeek, and G. T. Manley, “Clinical trials in traumatic brain injury: past experience and current developments,” Neurotherapeutics, vol. 7, no. 1, pp. 115–126, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. R. Vink and A. J. Nimmo, “Multifunctional drugs for head injury,” Neurotherapeutics, vol. 6, no. 1, pp. 28–42, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. D. J. Loane and A. I. Faden, “Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies,” Trends in Pharmacological Sciences, vol. 31, no. 12, pp. 596–604, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. U. Rutishauser, J. P. Thiery, and R. Brackenbury, “Mechanisms of adhesion among cells from neural tissues of the chick embryo,” Proceedings of the National Academy of Sciences of the United States of America, vol. 73, no. 2, pp. 577–581, 1976. View at Scopus
  12. V. Soroka, C. Kasper, and F. Poulsen, “Structural biology of NCAM,” Advances in Experimental Medicine and Biology, vol. 663, pp. 3–22, 2010. View at Publisher · View at Google Scholar · View at Scopus
  13. J. Nielsen, N. Kulahin, and P. S. Walmod, “Extracellular protein interactions mediated by the neural cell adhesion molecule, NCAM: heterophilic interactions between NCAM and cell adhesion molecules, extracellular matrix proteins, and viruses,” Advances in Experimental Medicine and Biology, vol. 663, pp. 23–53, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. V. V. Kiselyov, V. Soroka, V. Berezin, and E. Bock, “Structural biology of NCAM homophilic binding and activation of FGFR,” Journal of Neurochemistry, vol. 94, no. 5, pp. 1169–1179, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. V. V. Kiselyov, “NCAM and the FGF-Receptor,” Advances in Experimental Medicine and Biology, vol. 663, pp. 67–79, 2010. View at Publisher · View at Google Scholar
  16. M. Noble, M. Albrechtsen, and C. Moller, “Glial cells express N-CAM/D2-CAM-like polypeptides in vitro,” Nature, vol. 316, no. 6030, pp. 725–728, 1985. View at Scopus
  17. E. T. Cox, L. H. Brennaman, K. L. Gable et al., “Developmental regulation of neural cell adhesion molecule in human prefrontal cortex,” Neuroscience, vol. 162, no. 1, pp. 96–105, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. E. Gascon, L. Vutskits, and J. Z. Kiss, “Polysialic acid-neural cell adhesion molecule in brain plasticity: from synapses to integration of new neurons,” Brain Research Reviews, vol. 56, no. 1, pp. 101–118, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. V. Duveau and J. M. Fritschy, “PSA-NCAM-dependent GDNF signaling limits neurodegeneration and epileptogenesis in temporal lobe epilepsy,” European Journal of Neuroscience, vol. 32, no. 1, pp. 89–98, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. L. Vutskits, E. Gascon, and J. Z. Kiss, “Removal of PSA from NCAM affects the survival of magnocellular vasopressin- and oxytocin-producing neurons in organotypic cultures of the paraventricular nucleus,” European Journal of Neuroscience, vol. 17, no. 10, pp. 2119–2126, 2003. View at Publisher · View at Google Scholar · View at Scopus
  21. L. Vutskits, E. Gascon, E. Zgraggen, and J. Z. Kiss, “The polysialylated neural cell adhesion molecule promotes neurogenesis in vitro,” Neurochemical Research, vol. 31, no. 2, pp. 215–225, 2006. View at Publisher · View at Google Scholar · View at Scopus
  22. E. Gascon, L. Vutskits, B. Jenny, P. Durbec, and J. Z. Kiss, “PSA-NCAM in postnatally generated immature neurons of the olfactory bulb: a crucial role in regulating p75 expression and cell survival,” Development, vol. 134, no. 6, pp. 1181–1190, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. E. Gascon, L. Vutskits, and J. Z. Kiss, “The role of PSA-NCAM in adult neurogenesis,” Advances in Experimental Medicine and Biology, vol. 663, pp. 127–136, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. A. K. Petridis, A. El Maarouf, and U. Rutishauser, “Polysialic acid regulates cell contact-dependent neuronal differentiation of progenitor cells from the subventricular zone,” Developmental Dynamics, vol. 230, no. 4, pp. 675–684, 2004. View at Publisher · View at Google Scholar · View at Scopus
  25. D. L. Brody, C. Mac Donald, C. C. Kessens et al., “Electromagnetic controlled cortical impact device for precise, graded experimental traumatic brain injury,” Journal of Neurotrauma, vol. 24, no. 4, pp. 657–673, 2007. View at Publisher · View at Google Scholar · View at Scopus
  26. R. E. Watson, S. J. Wiegand, and R. W. Clough, “Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology,” Peptides, vol. 7, no. 1, pp. 155–159, 1986. View at Scopus
  27. C. Culmsee, C. Zhu, S. Landshamer et al., “Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia,” Journal of Neuroscience, vol. 25, no. 44, pp. 10262–10272, 2005. View at Publisher · View at Google Scholar · View at Scopus
  28. N. Plesnila, S. Zinkel, D. A. Le et al., “BID mediates neuronal cell death after oxygen/glucose deprivation and focal cerebral ischemia,” Proceedings of the National Academy of Sciences of the United States of America, vol. 98, no. 26, pp. 15318–15323, 2001. View at Publisher · View at Google Scholar · View at Scopus
  29. S. Spijker, “Dissection of rodent brain regions,” Neuromethods, vol. 57, pp. 13–26, 2011. View at Publisher · View at Google Scholar · View at Scopus
  30. K. E. Saatman, K. J. Feeko, R. L. Pape, and R. Raghupathi, “Differential behavioral and histopathological responses to graded cortical impact injury in mice,” Journal of Neurotrauma, vol. 23, no. 8, pp. 1241–1253, 2006. View at Publisher · View at Google Scholar · View at Scopus
  31. J. W. Huh, A. G. Widing, and R. Raghupathi, “Midline brain injury in the immature rat induces sustained cognitive deficits, bihemispheric axonal injury and neurodegeneration,” Experimental Neurology, vol. 213, no. 1, pp. 84–92, 2008. View at Publisher · View at Google Scholar · View at Scopus
  32. L. Bonfanti, S. Olive, D. A. Poulain, and D. T. Theodosis, “Mapping of the distribution of polysialylated neural cell adhesion molecule throughout the central nervous system of the adult rat: an immunohistochemical study,” Neuroscience, vol. 49, no. 2, pp. 419–436, 1992. View at Publisher · View at Google Scholar · View at Scopus
  33. J. Nacher, G. Alonso-Llosa, D. Rosell, and B. McEwen, “PSA-NCAM expression in the piriform cortex of the adult rat. Modulation by NMDA receptor antagonist administration,” Brain Research, vol. 927, no. 2, pp. 111–121, 2002. View at Publisher · View at Google Scholar · View at Scopus
  34. C. M. Chuong and G. M. Edelman, “Alterations in neural cell adhesion molecules during development of different regions of the nervous system,” Journal of Neuroscience, vol. 4, no. 9, pp. 2354–2368, 1984. View at Scopus
  35. S. Soares, Y. Von Boxberg, M. Ravaille-Veron, J. D. Vincent, and F. Nothias, “Morphofunctional plasticity in the adult hypothalamus induces regulation of polysialic acid-neural cell adhesion molecule through changing activity and expression levels of polysialyltransferases,” Journal of Neuroscience, vol. 20, no. 7, pp. 2551–2557, 2000. View at Scopus
  36. R. A. Prosser, U. Rutishauser, G. Ungers, L. Fedorkova, and J. D. Glass, “Intrinsic role of polysialylated neural cell adhesion molecule in photic phase resetting of the mammalian circadian clock,” Journal of Neuroscience, vol. 23, no. 2, pp. 652–658, 2003. View at Scopus
  37. L. Bonfanti, “PSA-NCAM in mammalian structural plasticity and neurogenesis,” Progress in Neurobiology, vol. 80, no. 3, pp. 129–164, 2006. View at Publisher · View at Google Scholar · View at Scopus
  38. D. K. Ditlevsen, G. K. Povlsen, V. Berezin, and E. Bock, “NCAM-induced intracellular signaling revisited,” Journal of Neuroscience Research, vol. 86, no. 4, pp. 727–743, 2008. View at Publisher · View at Google Scholar · View at Scopus
  39. M. I. Domínguez, J. M. Blasco-Ibáñez, C. Crespo, A. I. Marqués-Marí, and F. J. Martínez-Guijarro, “Calretinin/PSA-NCAM immunoreactive granule cells after hippocampal damage produced by kainic acid and DEDTC treatment in mouse,” Brain Research, vol. 966, no. 2, pp. 206–217, 2003. View at Publisher · View at Google Scholar · View at Scopus
  40. E. Lee and H. Son, “Adult hippocampal neurogenesis and related neurotrophic factors,” BMB Reports, vol. 42, no. 5, pp. 239–244, 2009. View at Scopus
  41. V. Duveau, S. Arthaud, A. Rougier, and G. Le Gal La Salle, “Polysialylation of NCAM is upregulated by hyperthermia and participates in heat shock preconditioning-induced neuroprotection,” Neurobiology of Disease, vol. 26, no. 2, pp. 385–395, 2007. View at Publisher · View at Google Scholar · View at Scopus
  42. M. S. L. Hammond, C. Sims, K. Parameshwaran, V. Suppiramaniam, M. Schachner, and A. Dityatev, “Neural cell adhesion molecule-associated polysialic acid inhibits NR2B-containing N-methyl-D-aspartate receptors and prevents glutamate-induced cell death,” Journal of Biological Chemistry, vol. 281, no. 46, pp. 34859–34869, 2006. View at Publisher · View at Google Scholar · View at Scopus
  43. M. C. Amoureux, B. A. Cunningham, G. M. Edelman, and K. L. Crossin, “N-CAM binding inhibits the proliferation of hippocampal progenitor cells and promotes their differentiation to a neuronal phenotype,” Journal of Neuroscience, vol. 20, no. 10, pp. 3631–3640, 2000. View at Scopus
  44. U. Rutishauser, “Polysialic acid in the plasticity of the developing and adult vertebrate nervous system,” Nature Reviews Neuroscience, vol. 9, no. 1, pp. 26–35, 2008. View at Publisher · View at Google Scholar · View at Scopus
  45. G. B. Kaplan, J. J. Vasterling, and P. C. Vedak, “Brain-derived neurotrophic factor in traumatic brain injury, post-traumatic stress disorder, and their comorbid conditions: role in pathogenesis and treatment,” Behavioural Pharmacology, vol. 21, no. 5-6, pp. 427–437, 2010. View at Publisher · View at Google Scholar · View at Scopus
  46. C. Cassens, R. Kleene, M. F. Xiao et al., “Binding of the receptor tyrosine kinase TrkB to the Neural Cell Adhesion Molecule (NCAM) regulates phosphorylation of NCAM and NCAM-dependent neurite outgrowth,” Journal of Biological Chemistry, vol. 285, no. 37, pp. 28959–28967, 2010. View at Publisher · View at Google Scholar · View at Scopus
  47. A. Nykjaer, T. E. Willnow, and C. M. Petersen, “p75NTR—Live or let die,” Current Opinion in Neurobiology, vol. 15, no. 1, pp. 49–57, 2005. View at Publisher · View at Google Scholar · View at Scopus
  48. R. Seidenfaden, A. Krauter, and H. Hildebrandt, “The neural cell adhesion molecule NCAM regulates neuritogenesis by multiple mechanisms of interaction,” Neurochemistry International, vol. 49, no. 1, pp. 1–11, 2006. View at Publisher · View at Google Scholar · View at Scopus
  49. Y. Zhang, X. Zhang, J. Yeh, P. Richardson, and X. Bo, “Engineered expression of polysialic acid enhances Purkinje cell axonal regeneration in L1/GAP-43 double transgenic mice,” European Journal of Neuroscience, vol. 25, no. 2, pp. 351–361, 2007. View at Publisher · View at Google Scholar · View at Scopus
  50. M. P. Morel, I. Dusart, and C. Sotelo, “Sprouting of adult Purkinje cell axons in lesioned mouse cerebellum: 'Non-permissive' versus 'permissive' environment,” Brain Cell Biology, vol. 31, no. 8-9, pp. 633–647, 2002. View at Scopus
  51. R. A. Asher, D. A. Morgenstern, L. D. F. Moon, and J. W. Fawcett, “Chondroitin sulphate proteoglycans: inhibitory components of the glial scar,” Progress in Brain Research, vol. 132, pp. 611–619, 2001. View at Publisher · View at Google Scholar · View at Scopus
  52. A. A. Lavdas, I. Franceschini, M. Dubois-Dalcq, and R. Matsas, “Schwann cells genetically engineered to express PSA show enhanced migratory potential without impairment of their myelinating ability in vitro,” GLIA, vol. 53, no. 8, pp. 868–878, 2006. View at Publisher · View at Google Scholar · View at Scopus
  53. C. Bachelin, V. Zujovic, D. Buchet, J. Mallet, and A. Baron-Van Evercooren, “Ectopic expression of polysialylated neural cell adhesion molecule in adult Macaque Schwann cells promotes their migration and remyelination potential in the central nervous system,” Brain, vol. 133, no. 2, pp. 406–420, 2010. View at Publisher · View at Google Scholar · View at Scopus
  54. A. El Maarouf and U. Rutishauser, “Use of PSA-NCAM in repair of the central nervous system,” Advances in Experimental Medicine and Biology, vol. 663, pp. 137–147, 2010. View at Publisher · View at Google Scholar · View at Scopus
  55. A. El Maarouf, A. K. Petridis, and U. Rutishauser, “Use of polysialic acid in repair of the central nervous system,” Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 45, pp. 16989–16994, 2006. View at Publisher · View at Google Scholar · View at Scopus
  56. A. I. Maas, N. Stocchetti, and R. Bullock, “Moderate and severe traumatic brain injury in adults,” The Lancet Neurology, vol. 7, no. 8, pp. 728–741, 2008. View at Publisher · View at Google Scholar · View at Scopus