Widespread Structural and Functional Connectivity Changes in Amyotrophic Lateral Sclerosis: Insights from Advanced Neuroimaging Research
Figure 4
Increase of functional connectivity and lower structural connectivity in a population of ALS patients studied by Douaud et al. [22]. The spatial distribution of the significant increase of functional connectivity in patients (red-yellow scale: , corrected) corresponded to the areas where the patients had lower structural connectivity, evaluated by using tract-based spatial statistics and probabilistic tractography, in comparison to healthy controls (in blue, thresholded at 10 streamlines of difference on average) (derived from Douaud et al. [22]). By permission of Oxford University Press.
