Review Article

What We Know and Would Like to Know about CDKL5 and Its Involvement in Epileptic Encephalopathy

Figure 3

Cdkl5 expression patterning in the adult male mouse brain (C57BL/6J, postnatal day 56). Images are collected from the Allen Brain Atlas website (http://www.brain-map.org/; probe name RP_051219_02_C01; experiment ID 74000486 for sagittal samples, experiment ID 75042239 for coronal samples). Each Nissl-stained section is coupled by a quantitative in situ hybridization screening at different sectioning levels. The color bar in (a) might be used to follow transcription level intensity. (b), (c), (d), (e), (f), and (g) are representative of different brain levels, therefore, different brain areas; in particular: cg: cingulated cortex, st: striatum, pc: piriform cortex, hyp: hypothalamus, ec: entorhinal cortex, dg: dentate gyrus, ca1,2,3: hippocampal CA fields, vta: ventral tegmental area, gn: geniculate nuclei, sn: substantia nigra, lc: locus ceruleus, pc: Purkinje cells.
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