Activity-Dependent Callosal Axon Projections in Neonatal Mouse Cerebral Cortex
Figure 3
Effects of expression of several ion channels on callosal axon projections. (a) Expression of a dominant-negative KCNQ2 K+ channel [94] does not influence callosal axon development. (b) A disease-causing, dominant-negative Kir2.1 mutant does not impair callosal axon projections. (c) Expression of a gain-of-function Kir2.1 mutant in callosal projection neurons impedes their axonal projections. Scale bar, 200 μm. Adapted from [38].
