Effects of Antipsychotics on Dentate Gyrus Stem Cell Proliferation and Survival in Animal Models: A Critical Update

Table 2

Survey of the effects of neuroleptics on hippocampal neurogenesis.

Model	Effect on neuroleptics on neurogenesis in the hippocampus	Literature
Vitamin D deficiency	Haloperidol ↑	[29]
Maternal infection	Risperidone ↑	[28]
	Clozapine ∅↗	[64]
Ketamine	Haloperidol ↑*	[30]
	Risperidone ↑*	[30]
Phencyclidine	Risperidone ∅	[65]
	Clozapine ↑	[66]
Postnatal lesion of; ventral hippocampus	Haloperidol ∅↗	[67], indirect

Ø: no effect, ↑∶ increase,  ↗∶ increase after application of low doses, *: cell survival.