852423.fig.004a
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852423.fig.004b
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852423.fig.004c
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852423.fig.004d
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852423.fig.004e
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852423.fig.004f
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852423.fig.004g
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852423.fig.004h
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Figure 4: At a young age, the subjects made a significant number of unsuccessful attempts to grab the horizontal bar with their hands and would transverse the bar upside down (a and e). The subjects would typically overreach the bar with their arms and glide their arms across the bar until their hands were able to latch on (white arrows in a and b). The lower limb also had difficulty latching onto the bar during the first two postoperative years after the surgery (black arrow in panels a and g). At two years of age, the monkeys began not to attempt to use the contralateral upper limb to transverse the bar (black arrows in panel c). Typically the subject would successfully use the affected hind limb (black arrow in panels d and h) and would not attempt to use the front limb (white arrow in panels d and f) to transverse the horizontal bar. By 2 years after surgery the subjects were able to walk upright across the bar. Dashed line (e and g) represents the expected value for a normal monkey. % successful was determined as successful latches (hand or foot)/total attempts to latch onto the horizontal bar. The ipsilateral side of the body acts as an internal control for normal motor movements and did not show any paretic movements. Years 1, 2, and 3 refer to the age of the infant-lesioned subjects at testing which also corresponds to the years after lesion. For the adult-lesioned subjects, year 4 refers to the number of years after initial surgery. Adapted from [14].