Subthalamic hGAD65 Gene Therapy and Striatum TH Gene Transfer in a Parkinson’s Disease Rat Model
Figure 7
Immunohistochemistry of hGAD65 in the STN (DAB, bar = 100 μm). A large number of hGAD65-positive cells are observed in the left STN (a, c, and d) of rAAV2-hGAD65 groups, but there are no positive cells in either hemispheres of the TH group (b). The number of hGAD65-positive cells decreased according to posttreatment time: 4 weeks (a), 8 weeks (c), and 16 weeks (d).
