Review Article
Brain Reorganization following Intervention in Children with Congenital Hemiplegia: A Systematic Review
Table 1
Population and study design.
| | Study | Design | Patients | M : F | Age | Diagnosis: congenital U-CP | Lesion/etiopathogenesis | Type of reorganization |
| | [13] | Case series | 5* | n/a | 7–13 ys |
4R-CP, 1bilateralCP* | n/a | n/a | | [14] | Case series | 10 | 6 : 4 | 2.1–7.6
() | 8R-CP; 2L-CP | 3L-FP; 4L-PV; 1R-F;
1L-FT; 1R-FP | n/a | | [15] | Case series | 10 | 4 : 6 | 7–14 ys
() | 4L-CP; 6R-CP | 3 malformative,
3 prenatal, 1 connatal,
2 early acquired, 1 n/a | n/a | | [16] | Case series | 3 | 2 : 1 | 13–15 ys | R-CP | 2 patients: perinatal stroke,
1 patient: IVH | n/a | | [17] | Case series | 10 | 5 : 5 | 10–30 ys
(median 14 ys) | 6R-CP; 4L-CP | unilateral cortical-subcortical infarction in the MCA territory | 7/10 ipsilesional
3/10 mixed | | [18] | Case series | 7 | 3 : 4 | 10–30 ys
(median 16 ys) | 5R-CP; 2L-CP | unilateral cortical-subcortical infarction in the MCA territory | ipsilesional | | [19] | Case series divided into: contralesional, ipsilesional | 16
9/16
7/16 | 8 : 8
5 : 4
3 : 4 | 10–31 ys
11–31 ys
10–30 ys | 6L-CP, 10R-CP
4L-CP, 5R-CP
2L-CP, 5R-CP | unilateral cortical-subcortical infarction in the MCA territory | 9/16 contralesional
7/16 ipsilesional |
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A participant had bilateral involvement with right arm sparing; assessed by Transcranial Magnetic Stimulation (TMS). Abbreviations: M: male; F: female; ys: years; L: left; R: right; U-CP: unilateral cerebral palsy, IVH: intraventricular hemorrhage; MCA: middle cerebral artery; FP: frontoparietal; PV: periventricular; F: frontal; TP: temporal-parietal; CIMT: constraint-induced movement therapy; VR: virtual reality; NDT: neurodevelopmental treatment; OT: occupational therapy; n/a: not available.
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