Microglia and Synapse: Interactions in Health and Neurodegeneration
Figure 1
Ultrastructural relationships between microglia and synaptic elements in physiological conditions. Electron microscopy examples of Iba1-immunostained microglial (m+) cell body (a), as well as large (b) and small (c) processes, showing direct juxtaposition with axonal terminals (in blue), dendritic spines (in pink), astrocytic processes (in green), and synaptic cleft (arrow) in adolescent mouse visual cortex. d: dendrite; N: nucleus; p: perikaryon; asterisks: extracellular space. Scale bars: 250 nm. Reproduced from Tremblay et al. [30].
