Splenium of Corpus Callosum: Patterns of Interhemispheric Interaction in Children and Adults
Figure 2
Interhemispheric integration effects as revealed by fMRI activation and dynamic causal modeling. (a) Statistical maps of the CG > NG contrast for the children and adults groups superimposed on a pial surface of a standard brain in MNI space (bottom view). In both groups, an increase of BOLD response is located within the lingual/fusiform gyri, but in the adults it is higher and more extensive. The center of each cluster served to define the V3 location for DCM analysis in each group. (b) Intrinsic and modulatory connections in children and adults. Gray/blue-filled circles symbolize the brain regions involved in the modeled network. They are located in the left and right primary visual cortex (V1L and V1R, resp.) and in the left and right V3v (V3L and V3R, resp.). Arrows between the circles stand for the bidirectional intrinsic/modulatory connections. Dashed arrows designate nonsignificant connections; gray arrows, significant but not changing with age; black arrows, significant and changing with age. The average estimate of the strength of connection in Hertz is shown alongside the respective arrow.
