Enhanced Expression of NR2B Subunits of NMDA Receptors in the Inherited Glaucomatous DBA/2J Mouse Retina

Figure 3

Changes in expression of Cdk5, p35 of DBA/2J mice at various ages. (a) Representative immunoblots showing the changes of Cdk5 and p35 levels in DBA/2J and C57BL/6 mice at ages of 3, 6, 9, and 12 months. ((b), (c)) Bar chart showing the average densitometric quantification of immunoreactive bands of Cdk5 (b) and p35 (c) in DBA/2J and C57BL/6 mice at ages of 3, 6, 9, and 12 months, respectively. ^∗∗∗𝑃<0.001 versus 3-month-old C57BL/6 mice; ^##𝑃<0.01 and ^###𝑃<0.001 versus 3-month-old DBA/2J; ^&&&𝑃<0.001 versus age-matched C57BL/6 mice.

(a)

(b)

(c)