Review Article

Neurogenesis, Exercise, and Cognitive Late Effects of Pediatric Radiotherapy

Figure 1

Irradiation of the developing (PND28) rat brain results in visibly decreased brain size in adulthood. Note that a 20 Gy total dose of X-ray radiation resulted in a smaller brain when it was administered as a single dose. A fractionated dose (4 Gy/d for 5 days) was less detrimental to brain size.
698528.fig.001