Activation of Glycine and Extrasynaptic GABA_A Receptors by Taurine on the Substantia Gelatinosa Neurons of the Trigeminal Subnucleus Caudalis

Figure 4

Inhibition of taurine-induced membrane depolarization and inward current by strychnine on SG neurons of Vc. (a), (c) Representative traces showing the taurine-induced membrane depolarization and taurine-induced inward current were blocked by strychnine (2 μM), a glycine receptor (GlyR) antagonist. (b), (d) Bar graphs showing the comparisons of mean relative membrane potential and inward current changed by the taurine alone and in the presence of strychnine (*𝑃<0.05, **𝑃<0.01).

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