Presynaptic Glycine Receptors Increase GABAergic Neurotransmission in Rat Periaqueductal Gray Neurons

<table>Effects of glycine on glutamatergic sEPSCs. (a) A typical trace of glutamatergic sEPSCs observed before, during, and after application of 100 <i>μ</i>M glycine. Insets represent typical traces with an expanded time scale (left) and single sEPSCs indicated by symbols (right). (b) Cumulative probability distribution for interevent interval (A) and current amplitude (B) of glutamatergic sEPSCs. 191 for control (thin lines) and 292 events for glycine (thick lines) were plotted. Insets column represents mean and SEM from 12 neurons. Dotted lines represent the relative control of basal frequency and amplitude of sEPSCs. **<svg height="11.375" id="M25" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>; n.s.: not significant.</table>

Neural Plasticity

fig2

Figure 2

Figure 2: Presynaptic Glycine Receptors Increase GABAergic Neurotransmission in Rat Periaqueductal Gray Neurons 