System Consolidation of Spatial Memories in Mice: Effects of Enriched Environment

Figure 5

c-Fos protein expression in V1 and M2. M2: two-way ANOVA post hoc analysis Holm-Sidak method, HC-SC versus HC-EE, 𝑃=0.416; statistical significance for EE versus HC-EE at 20, 30, and 50 days. Statistical difference between EE and SC at 1 day, 𝑃=0.288; at 10 days, 𝑃=0.154; at 20, 30, and 50 days, 𝑃<0.05. Statistical differences within EE group were found between 10 and 20 days, and 1 day versus 20, 30, and 50 days, all 𝑃 values < 0.05. V1: two-way ANOVA post hoc analysis Holm-Sidak method, HC-SC versus HC-EE 𝑃=0.907; statistical significance for EE versus HC-EE at 20, 30, and 50 days, and for SC versus HC-SC at 20, 30, and 50 days, all 𝑃 values < 0.05. Statistical significance for factor day was found between 1 day versus 20, 30, and 50 days, and 10 days versus 20, 30, and 50 days, all 𝑃 values < 0.05. ^■Statistical significance between EE and HC-EE; ^□statistical significance between SC and HC-SC; ^∗=statistical significance between EE and SC; ^∘statistical significance for factor day ^§=statistical significance within EE group; error bars = s.e.m.