Protective Effects of Ginkgo biloba Extract EGb 761 against Noise Trauma-Induced Hearing Loss and Tinnitus Development

Figure 1

Timeline of the experiments. Two weeks prior to trauma (yellow bar) oral application of vehicle or EGb 761 was performed on a daily basis. Pretrauma measurements included behavioral startle responses (turquoise; hearing threshold and gap-noise tinnitus paradigms), ABR measurements (dark green), and electrophysiological recordings in auditory cortex (light green) both under anesthesia. After the acoustic trauma the measurements were repeated within the first seven days after the trauma.