Hippocampal Neurogenesis and Antidepressive Therapy: Shocking Relations

Figure 1

Differentiation and maturation of adult neural stem cells. The process from stem cell division to the fully integrated mature neuron in the dentate gyrus takes approximately 30 days in rodents. Specific markers characterize the various maturation stages (e.g., DCX for neuroblasts). Experimental ECS or pharmacological treatments can influence neurogenesis at various stages; experimental ECS is also reported to activate quiescent stem cells.