Research Article

Neural Plasticity of Mild Tinnitus: An fMRI Investigation Comparing Those Recently Diagnosed with Tinnitus to Those That Had Tinnitus for a Long Period of Time

Table 6

Local maxima for the region-of-interest (ROI) independent sample -tests in the emotion task experiment. Between-group independent sample -tests using ROI analysis comprised of amygdala, insula, parahippocampus, and auditory cortex (Brodmann areas 42, 41, and 22) were conducted. Regions are listed in Montreal Neurological Institute (MNI) coordinates. Brodmann areas are also provided (before determining the Brodmann areas, the MNI coordinates were converted to Talairach coordinates). Statistical threshold was set at FWE corrected for multiple comparisons ( indicates significance at cluster level only). L: left; R: right.

ContrastMNI coordinates
, ,
scoreCluster
mm3
Gyrus (Brodmann area)

LTIN > RTIN (P > N)50, −42, 184.6634R. superior temporal gyrus (BA 22)
LTIN > RTIN (U > N)No suprathreshold voxels
RTIN > LTIN (P > N)No suprathreshold voxels
RTIN > LTIN (U > N)−32, −20, 144.46216L. insula (BA 13)