Research Article

Normal Metabolic Levels in Prefrontal Cortex in Euthymic Bipolar I Patients with and without Suicide Attempts

Table 2

Medial orbital prefrontal cortex metabolic levels between bipolar patients with and without suicide attempt and healthy controls (mmol/l ± SD).

Metabolic levelsBD I patientsHC Statistics
Suicidal
= 17
mean (SD)
Nonsuicidal
= 19
mean (SD)
= 16
mean (SD)

NAA2.79 ± 0.582.95 ± 0.583.12 ± 0.54,
Myo-inositol0.88 ± 0.420.97 ± 0.420.93 ± 0.41,
Choline1.32 ± 0.371.36 ± 0.421.27 ± 0.31,
Creatine1.53 ± 0.391.70 ± 0.531.63 ± 0.43,
NAA/creatine1.86 ± 0.361.85 ± 0.391.93 ± 0.51,
Choline/creatine0.86 ± 0.170.81 ± 0.140.78 ± 0.11,
Myo-inositol/creatine0.61 ± 0.310.63 ± 0.350.59 ± 0.27,
Choline2.79 ± 0.582.95 ± 0.583.12 ± 0.54,
Creatine0.88 ± 0.420.97 ± 0.420.93 ± 0.41,

Significant at the 0.05 level (2-tailed).
Degrees of freedom = 1.
NAA: N-acetyl-aspartate.
HC: Healthy controls.