The Morphofunctional Effect of the Transplantation of Bone Marrow Stromal Cells and Predegenerated Peripheral Nerve in Chronic Paraplegic Rat Model via Spinal Cord Transection

Figure 6

Fluorescence intensity analysis. Panels (a) and (b), expression of GAP-43: in both areas of the SC, a significant difference can be observed in the FG, PPN, and PPN + BMSCs groups compared to the Control group (Kruskal-Wallis test, ) as well as a significant difference in the treatment groups compared to the FG group (Mann-Whitney test, ). Panels (c) and (d), expression of Neuritin: it can be observed that the treatment groups obtained a significant difference when they are compared to the Control and FG groups (Kruskal-Wallis test and Mann-Whitney test, ). Panels (e) and (f), expression of PBM in the SC: in both areas, a significant difference is observed between the treated groups and the Control and FG groups (Kruskal-Wallis test and Mann-Whitney test, ); furthermore, in the distal zone, a significant difference can be observed between the PPN + BMSCs group compared with the PPN group (Mann-Whitney test, ). * is the difference with Kruskal-Wallis , and ** is the difference with -MANN .

(a) GAP-43 expression in the rostral zone

(b) GAP-43 expression in the caudal zone

(c) Neuritin expression in the rostral zone

(d) Neuritin expression in the caudal zone

(e) BMP expression in the rostral zone

(f) BMP expression in the caudal zone