Contralateral Metabolic Activation Related to Plastic Changes in the Spinal Cord after Peripheral Nerve Injury in Rats

Figure 1

Development of mechanical allodynia in rats with injury to the tibial and sural nerves. Response rate to a von Frey filament was used as an index of mechanical allodynia. Data were expressed as means ± S.E.M. Abscissa was marked as Pre for preoperative time and D for postoperative days (Sham: sham-operated control rats, Injured: neuropathic rats). Asterisks () indicate significant differences compared to preoperative values, according to Friedman’s repeated ANOVA on ranks followed by Dunnett’s multiple comparison test (, ).