Spinal Cord Hemisection Facilitates Aromatic L-Amino Acid Decarboxylase Cells to Produce Serotonin in the Subchronic but Not the Chronic Phase

Figure 1

5-HT-immunoreactive (IR) nerve fibers in the intermediate zone in the sacrocaudal spinal cord on the injured and uninjured side in different animal groups. (a–d) Photomicrographs of 5-HT-IR fibers in 5-day untreated group (a) and 5-HTP plus carbidopa treated group (b) and in 60-day untreated group (c) and 5-HTP plus carbidopa treated group (d). Dashed line represents the midline in each horizontal section. CC: central canal. Arrows in (b) and (d) indicate 5-HT-immunoreactive cells. Scale bar in (a), 100 μm. (e) Quantitative data of the density of 5-HT-IR fibers in different animals groups. , .

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