Research Article
Spinal Cord Hemisection Facilitates Aromatic L-Amino Acid Decarboxylase Cells to Produce Serotonin in the Subchronic but Not the Chronic Phase
Table 1
Summary of the results from the different animal groups.
| Group | Number of animals | Spinal cord side | Density of 5-HT fibers in IMZ1 (% of analyzed area) | Density of 5-HT fibers in VH2 (% of analyzed area) | Density of AADC cells (number of cells/analyzed section) | Density of 5-HT cells (% of AADC cells) |
| 5-day control |
5 | Injured | 0.89 ± 0.48 | 1.19 ± 0.51 | 19.99 ± 3.83 | 0 | Uninjured | 3.80 ± 1.22 | 5.02 ± 1.21 | 22.37 ± 7.11 | 0 |
| 5-day 5-HTP + carbidopa |
8 | Injured | 1.26 ± 0.78 | 0.73 ± 0.18 | 19.36 ± 8.78 | 42.52 ± 19.15 | Uninjured | 4.20 ± 1.82 | 3.13 ± 0.61 | 15.08 ± 7.61 | 25.86 ± 17.81 |
| 60-day control |
6 | Injured | 0.36 ± 0.06 | 0.59 ± 0.38 | 8.83 ± 3.45 | 0 | Uninjured | 3.24 ± 1.24 | 2.72 ± 1.25 | 7.10 ± 3.73 | 0 |
| 60-day 5-HTP + carbidopa |
6 | Injured | 0.78 ± 0.34 | 0.35 ± 0.08 | 11.42 ± 5.94 | 15.98 ± 18.72 | Uninjured | 2.41 ± 1.16 | 1.54 ± 0.46 | 10.85 ± 4.80 | 9.57 ± 15.00 |
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IMZ: intermediate zone; 2VH: ventral horn.
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